Low levels of several of the vitamins are very often associated with anxiety and panic disorder.
Perhaps the most important is vitamin B1. Its deficiencies are detected in the largest percentage of patients, and supplementation can produce the best results. In one clinical trial, most people were completely cured of anxiety in just a few weeks. Its levels drop due to alcohol abuse, inflammatory processes in the body and, of course, poor diet. There’s no need to mess around with tests that cost more than the supplement, no need to analyze symptoms that overlap with those of hundreds of diseases, and with a slight deficiency simply won’t occur. Best to just buy a supplement.
Its levels drop a lot when you drink alcohol, but one study draws attention. It measured thiamine levels in people with generalized anxiety disorder who never abused alcohol. As it turned out, they had an average level of 25 nmol/l, the normal level in a healthy person should be between 70 and 180. Supplementation with high doses made the patients completely cured, they gave up beta-blockers and tranquilizers.
https://www.scirp.org/journal/PaperInformation.aspx?paperID=7555
The same goes for vitamin b6. Here the cost of a supplement is about $1. Low levels are detected often enough that every ill person should try it “just in case”. Attention: doses over 100 mg a day can be slightly toxic.
B12 – here it is worth doing a blood test to determine its level (note, you have to wait at least 2 weeks since you took any supplements). If the level has dropped a lot, there is always a reason for it and it should be determined. The result should be in the middle of the normal range, so even if we do not have a deficiency, but it came out near the lower limit, it is good to supplement this vitamin. Due to the nature of its absorption, only very high doses, on the order of tens of thousands of percent of the requirement, are effective. In our intestines about 1% of this amount will be absorbed anyway.
Article by me on supplementing B12:
https://healthytreatment.org/2022/02/18/b12-supplementation/
If you’re supplementing with B vitamins, it’s important to remember that they work synergistically, so you need to take them all at once, otherwise an excess of one can flush out the others. Fortunately, a package of B complex costs less than $2 where I live.
D3 deficiency is very common. In this case also tests are pointless, I guarantee that everyone is deficient in winter and almost no one in summer. You can easily save this $100 and spend it on something pleasant. If you don’t tan, or use sunscreen, you almost certainly have a very big problem. You should use doses of 2-4 thousand units a day in winter, 0.5-1 thousand in summer. People who suspect severe deficiency (very rarely going out in the sun) should take doses much, much higher at least for the first few weeks. During supplementation it is necessary to supplement magnesium in parallel, otherwise we will quite quickly lead to symptoms of magnesium deficiency, as it is consumed to activate D3. If alarming symptoms appear, such as frequent urination, increased nervousness, constipation, it is necessary to discontinue D3 and increase the doses of magnesium, possibly adding very high doses of vitamin A.